I’m sure it will be possible.  Check out this thread:  http://lists.katipo.co.nz/public/koha/2009-May/018195.html

If you haven’t done so yet, visit the Koha list archives at Nabble or another web forum. It makes it easy to search the archived posts to find similar topics under discussion: http://koha.1045719.n5.nabble.com/

I did an install on Fedora as my first trial of Koha and it worked fine. At that time I was more familiar with the Red Hat Linux distributions than Debian distributions. There was less documentation available (there is the install_fedora7 doc), and a few other things on the web, but I was able to find all the packages I needed. Most challenging was getting the Perl modules installed. Don’t know if that was because of Fedora or because it was really my first time to work with CPAN. Some of the modules I had to force install.

Since Koha uses Apache, php, perl and MySQL and these are all available for Centos, there is nothing inherent about the OS that would prohibit it.

I install Webmin as the first custom software after normal distribution updates. Then I use Webmin to configure all the server settings and manage the databases.

Marion